Who makes metformin?

Metformin, also known as glucophage, is a medication used to manage blood sugar levels in individuals with type 2 diabetes. It is one of the most commonly prescribed medications for type 2 diabetes globally because it reduces appetite and causes weight loss. So who makes this wonder drug? Let’s find out.

What Is Metformin And How Does It Work?

Metformin was initially discovered in the middle of the last century, but only started being used widely in the late 1970s when scientists realized its potential application as an anti-diabetic drug. The mechanism behind metformin consists of suppressing glucose production by helping cells to absorb glucose more efficiently from food before it hits the bloodstream.

Insight Into The Companies That Make Metformin

There are many pharma companies that produce metformin as part of their offerings worldwide. Some popular brands include Glucophage (Bristol Myers-Squibb), Fortamet (Akrimax Pharmaceuticals), Glumetza( Santarus/Salix), and Riomet among others.

Bristol-Myers Squibb

Bristol Myers-Squibb (BMS) is a global biopharmaceutical company headquartered in New York City that creates medicines for patients suffering from disorders like cancer, cardiovascular diseases or HIV/AIDS. BMS produces metformin under its brand name “Glucophage” primarily sold across North America & EU regions via pharmaceutical wholesalers/suppliers network and online retail pharmacies `

Akrimax Pharmaceuticals

Akrimax Pharmaceuticals LLC based out New Jersey was founded back in 2007 and holds expertise exclusively on metabolic therapies/products including fortamet (Extended –release tablets).

Sun Pharmaceutical Industries Ltd.

Sun pharmaceutical industries ltd., headquartered at Mumbai India operates manufacturing centers located worldwide alongside select key markets such as US, Canada; Mexico etc producing over-the-counter health related products and a range of non-prescription drugs. The company is among the world’s leading generics and speciality pharmaceuticals producer.

Production Of Metformin

Now that you know about these companies, let’s take a sneak peek into how they produce this so-called “magic” medication.

Synthetic Route

Metformin production or synthesis has multiple phase pathways involving catalytic, solvent-based reactions within automated/controlled laboratory settings. Here are some common process steps:
– Oxidation of methanol to formaldehyde using methane monooxygenase
– Attack piritolyl imine on ethylene diamine followed by reaction with hydrogen peroxide to get metformin

Manufacturing Plants And Process Controls

Pharmaceutical manufacturing procedures require strict guidelines set forth by government regulations for ensuring consistency in the final drug product. Each manufacturer must adhere to good manufacturing practices (GMP) when producing any drug which includes everything from facility temperature control measures, moisture levels measurements facilities, SOP’s(Quality control processes), clean rooms with HVAC systems etc. Everything is designed meticulously keeping minute details in mind down to instrumentation calibration & validation programs long before coming onto market shelves; because reliability is utmost goal as it relates critical health outcomes.

Conclusion

In conclusion, understanding who makes metformin and its production operation gives insight into what goes on behind-the-scenes before patients clutch their prescriptions day-in-day-out worldwide. Choosing your diabetes’ medication ultimately rests on your doctor however next time you pick up Glucophage/Fortamet(extended-release)/Glumetza/Riomet at pharmacy around corner remember many companies make possible such medicines everyday painstakingly following each step necessary under intense scrutiny through variety regulatory agencies involved monitoring quality performance thus making life-saving difference eventually overall while holding increasingly vital role figuring 21st century medicine economies out over time!

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