What’s the best blood thinner to take?

Blood thinners, also known as anticoagulant medications, are used to prevent dangerous blood clotting that can lead to strokes and heart attacks. However, with so many different types of blood thinners available on the market today, it can be difficult to determine which one is right for you. If you’re feeling confused or overwhelmed by all the options out there, fear not! In this article, we’ll guide you through everything you need to know about choosing the best blood thinner.

The Different Types of Blood Thinners

Before diving into which type of blood thinner might be best for you, let’s quickly go over what they actually do. Essentially, these medications prevent your blood from clotting too easily by inhibiting certain enzymes in your body that play a role in coagulation. Some common types of blood thinners include:


Warfarin (Coumadin) has been around since the 1950s and was once the most commonly prescribed anticoagulant medication on the market until newer drugs were developed. It works by blocking vitamin K-dependent clotting factors and preventing them from functioning properly.


Heparin is a fast-acting injectable medication that works by binding with and activating an enzyme called antithrombin III (ATIII). This enzyme then goes on to block various components involved in coagulation.


Direct oral anticoagulants (DOACs), also known as non-vitamin K antagonist oral anticoagulants (NOACs), are a newer class of drugs that have become increasingly popular over the last decade. Examples include apixaban (Eliquis), dabigatran (Pradaxa), edoxaban (Savaysa/Lixiana), and rivaroxaban(Xarelto).

DOACs work by directly inhibiting specific enzymes involved in blood clotting, such as thrombin and factor Xa.

Antiplatelet Agents

Antiplatelet agents, like aspirin or clopidogrel (Plavix), prevent platelets from sticking together to form clots. They are usually used for people who have had a recent heart attack or stroke, or who have been diagnosed with peripheral artery disease.

Factors That Influence Which Blood Thinner is Best For You

Now that you have a basic understanding of the different types of blood thinners available, let’s look at some factors that can help influence which medication may be best suited for you:

Medical History

Your medical history will play an important role in determining which blood thinner is right for you. Some medications interact poorly with certain pre-existing conditions, such as kidney disease or liver dysfunction. If you’ve undergone surgery recently (or plan on doing so soon), this could also affect which drug your doctor prescribes.

If you’re prone to falls or other accidents that could lead to bleeding (e.g., if you’re elderly), your doctor will need to take this into account when weighing up the benefits and risks of different anticoagulant options.

Cost & Insurance Coverage

Blood thinners can be costly depending on where you live and what type of insurance coverage / health care system exists. This can range from being quite affordable under one country’s public healthcare system (with free transport home after any hospital appointments – not joking!) . Your financial situation should be taken into consideration before deciding on an anticoagulant medication especially since DOACs tend to cost more than warfarin/ heparin-based drugs.

Personal Preferences

Just like each person has their own unique personality trait – they may also want their personal preferences considered whilst choosing the correct blood thinner! No really,(we kid- but it’s something doctors might say!) This may consist of things like the length of treatment, how often medication needs to be taken, if it’s oral or injected etc.

Other Medications

Some medications can interact negatively with blood thinners: a person on this type of medication should speak to their doctor(s) about whether any changes need to be made in terms of dosages etc.

Warfarin vs DOACs – Which One is Better?

When it comes down to warfarin vs DOACs, there’s no clear-cut answer that applies universally. However, here are some key factors and differences between the two:

How they’re Administered

Warfarin must be administered orally: patients who have trouble swallowing pills or remembering dosage timings might find this difficult/detrimental for their overall health (although- not limiting them from alternatives) .

DOACs come in pill form too but don’t require the same monitoring as warfarin -whose levels in blood & side effects must me monitored via weekly INR tests.

The administration methods at times depend with one’s medical state and prescribed approved medicines being useful within said conditions.

Interactions with Other Drugs

There are drugs that curb the effectiveness/safety profile when someone is taking either a NOAC (apixaban , dabigatran , edoxaban )or warfarin such as nonsteroidal anti-inflammatory drugs(NSAIDs), selective serotonin reuptake inhibitors(SSRIs)low-molecular weight heparins(LMWH), aspirins et al . Always check^1
if all medications you purchase off the counter/online require your healthcare provider’s green light.

And now time for bullet points as we compare both warfarin vs NOAC (Hell yeah!)

-Long half life
-Slow onset & offset
-Regular Blood Testing needed: (because of patient variability and drug-diet interactions)
-Many food-drug-negative interactions are well documented

  • Short half-life
    2-4 hours after administration
    high efficacy profile portrayed in NOAC clinical trials; with timings varying according to the intended bleeding sensitive area.
    -Lower risk of brain hemorrhaging/ intracranial bleeding for example
    Less need for monitoring compared to warfarin

When choosing between warfarin and a DOAC , healthcare providers will assess each patients needs first then decide if there is any significant preference from them, it may rely heavily on the patients individual medical history.

Common Side Effects of Anticoagulant Medications

Like all medications, blood thinners have various side effects that users should be aware of:

Minor Side Effects

The minor side effects associated with anticoagulant therapy vary by medication. Warfarin can cause nausea/vomiting or abdominal pain while DOACs might causerashes/headaches . Most people experience minimal/unnoticeable discomfort though!

Major Side Effects

Bleeding risks are obviously one major concern when taking any type of anticoagulation drugs.Patients who notice frequent nosebleeds or blood urine during treatment should contact their doctor immediately!

Blood thinners tend to slow down wound healing as was studied in an animal model^^^,therefore taking your doctors recommendation post-surgery seriously runs paramount.

Conclusion: Which Blood Thinner Should You Take?

Choosing the right blood thinner ultimately depends on several factors specific to each person. The choice could be affected by pre-existing conditions (such as kidney / liver issues), cost/ insurance coverage ; personal preferences such as frequency & oral / injected usage); and potential interaction(s) with other drugs.

To sum up ,Both warfarin and DOACs have their own set of advantages/disadvantages that should be taken into account. It is best to go for a medication which will suit your needs now- and where needed changed if necessary depending on how things progress or deteriorate.

As always before starting any blood thinning medication, take the time to speak with your doctor about all possible options regarding therapy selection, monitoring parameters (eg: INR testing) etc.,and what risks/ benefits you may encounter in taking such drugs regularly.

Happy coagulating!(or Anticoagulating!!?)!