What is the best medication for arthritis?

Arthritis can be a real pain in the… well, everywhere really. It’s no secret that this chronic condition causes inflammation and stiffness in your joints, making it difficult to move around with ease. Luckily, there are plenty of medications out there that can help manage these symptoms and make life a little more bearable. But which one is the best? Let’s start by taking a look at some of the options out there.

Nonsteroidal Anti-inflammatory Drugs (NSAIDs)

Nonsteroidal Anti-inflammatory Drugs or NSAIDs (because who has time to say all that?) are probably one of the most commonly prescribed medications for arthritis. They come in different forms such as pills or gels and work by reducing inflammation throughout your body. Some examples include:

  • Ibuprofen (Advil)
  • Naproxen (Aleve)
  • Celecoxib (Celebrex)

While NSAIDs may provide relief from pain and swelling, they can also lead to stomach ulcers, kidney damage, and nobody wants those!


Corticosteroids (we’ll just call them Steroids) are another option you might hear about when treating arthritis. Unlike NSAIDs which target inflammation throughout your whole body; steroids specifically act on certain areas causing larger swellings like bigfoot-size joint inflammations disappear faster than a magician’s trick.

But hey! That doesn’t mean you should just pop em like candy because synthetic cortisol production over time could cause harmful damage inside but under regulation won’t hurt!

Disease-modifying anti-rheumatic drugs (DMARDs)

Disease-modifying anti-rheumatic drugs (or DMARDs if you’re into abbreviations) slow down joint damage thereby suppressing inflammatory enzymes before they become active preventing further damages then restoring functionalities without actually fixing structures creating virtually no side effects. Ambrella, Voremica or anything like that…

DMARDs types are:

  • Methotrexate
  • Hydroxychloroquine
  • Sulfasalazine

They may not do what the steroids can do in terms of reducing inflammation quickly but if you play the long game; they’re worth investigating!

Biologic Drugs

Finally, we have biologic drugs (the wannabe superheros of joint pain relief) which essentially act as a stop signs signaling for cytokine police to stop inflammation and direct an immune response against arthritis through binding to certain molecules on cell surfaces meaning they address more specific problematic areas than NSAIDs.

Biologics include:

  • Adalimumab (Humira)
  • Etanercept (Enbrel)
  • Infliximab (Remicade)

But hey! They come at a cost with terrifying anti-allergic enforcers as possible side effect so get prescribed only when other medications fail!

Choosing The Best Medication For Arthritis…What If?

All these options and their potential positive attributes can be overwhelming….so let’s summarize it quick:

  • Steroids are useful for quick relief but overuse is harmful.
  • Nonsteroidal Anti-inflammatory Drugs help reduce chronic pain by lowering platelet aggregation
  • Disease-modifying Anti-rheumatic Drugs best work in the long term to suppress enzymes responsible for managing deeper-seated inflammatory responses.
  • Biologics disturb targeted interleukins and B plasma cells stimulating immune reactions aimed directly towards rejuvenating cartilage regrowth

Ultimately consult your physician who is better equipped at testing each medication’s efficacy based on current health conditions rather than seek comfort because none of this information outweighs after-effect risks arising from self-treatment.

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