What is silymarin used for?
Silymarin is used in the treatment of Chronic liver disease and Cirrhosis of the liver. Silymarin is an active principle obtained from milk thistle seed (Silybum marianum) .
What kind of Medicine is silymarin used for? Silymarin is used to treat hepatic dysfunction. It can also be used as supplementary medication for treating chronic inflammatory diseases such as cirrhosis liver toxicity and liver damage. Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person.
How is silymarin used to treat liver cirrhosis? According to open studies the long-term administration of silymarin significantly increased survival time of patients with alcohol induced liver cirrhosis. Based on the results of studies using methods of molecular biology, silymarin can significantly reduce tumor cell proliferation, angiogenesis as well as insulin resistance.
How much Silymarin is in milk thistle extract? Milk thistle extract has a high amount of silymarin (between 65–80%) that has been concentrated from the milk thistle plant. ).
What happens if you take too much silymarin? If you have taken more than the prescribed Silymarin tablets there is a chance of getting a harmful effect on your body’s functions. Overdose of a medicine can lead to some medical emergency. Silymarin can decrease how quickly those medications break down in the liver.
How is silymarin used in the treatment of liver disease?
How is silymarin used in the treatment of liver disease? In chronic liver diseases caused by oxidative stress (alcoholic and non-alcoholic fatty liver diseases, drug- and chemical-induced hepatic toxicity), the antioxidant medicines such as silymarin can have beneficial effect. Liver cirrhosis, non-alcoholic fatty liver and steatohepatitis are risk factors for hepatocellular carcinoma (HCC).
What kind of seeds are used for silymarin? Silymarin is an extract of milk thistle seeds. Silymarin has long been used in traditional medicine in many countries. It is claimed to have antifibrotic effects and protects the liver from fibrosis and other types of damage. However, the effects of Silymarin is not yet fully understood.
How does silymarin work as an antioxidant? 3. by inhibiting the enzyme lipoxygenase, which forms leukotrienes from oxidized polyunsaturated fats that damage the liver. 4. by acting as an antioxidant (silymarin is at least ten times more powerful than vitamin E). 5. by increasing the gluthathione (GSE) content of the liver.
How is silymarin used in preclinical studies? Preclinical studies by Varshosaz and coworkers 66 have shown that silymarin reduced MPO activity, TNF-α, and IL-6 levels in colon tissues, thereby ameliorating the histopathological features.