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What is dinoprostone?

May Treat: · · · ·

Brand Names: · ·

Drug Class: Abortifacients or Cervical Ripening Agents – Prostaglandin Analogs

Availability: Prescription Required

Pregnancy: Consult a doctor before using

Lactation: Consult a doctor before using

PrecautionsPrecautions

  • Drug is given by a nurse or a doctor.
  • Drug is given by a nurse or a doctor.
  • Tell doctor your complete medical history
  • Thaw slowly

  • For gel with prefilled applicator products : Insert into the vagina as directed. Do not use if labor began or if more than 1 baby. Causes uterine contractions. Review all drugs you are taking with your doctor. Your condition will be monitored by your Dr.
  • For insert, extended release products : Drug is given vaginally. Stay lying down for 2 hr.
  • For suppository, vaginal products : This drug is used to terminate pregnancy. Do not unwrap suppository until ready to insert. Remain lying down for 10 minutes after each dose. Do not use for more than 48 hours. Causes fever & flu like symptoms. Keep frozen prior to use.

What are side effects of Dinoprostone?Any warnings while using Dinoprostone?Does Dinoprostone interact with any drugs?Is Dinoprostone contraindicated for any condition?How to use Dinoprostone?What if you missed a dose of Dinoprostone?

For informational purposes only. Consult a medical professional for advice.

Reviewed by a panel of doctors. Source: First Databank

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  • People also askWhat does dinoprostone do to the human body?What does dinoprostone do to the human body?Dinoprostone is a natural substance (prostaglandin) that your body makes in preparation for labor. It softens and widens the opening of the womb and increases contractions.

    Precautions

    • Drug is given by a nurse or a doctor.
    • Drug is given by a nurse or a doctor.
    • Tell doctor your complete medical history
    • Thaw slowly

    • For gel with prefilled applicator products : Insert into the vagina as directed. Do not use if labor began or if more than 1 baby. Causes uterine contractions. Review all drugs you are taking with your doctor. Your condition will be monitored by your Dr.
    • For insert, extended release products : Drug is given vaginally. Stay lying down for 2 hr.
    • For suppository, vaginal products : This drug is used to terminate pregnancy. Do not unwrap suppository until ready to insert. Remain lying down for 10 minutes after each dose. Do not use for more than 48 hours. Causes fever & flu like symptoms. Keep frozen prior to use.

    What are side effects of Dinoprostone?Any warnings while using Dinoprostone?Does Dinoprostone interact with any drugs?Is Dinoprostone contraindicated for any condition?How to use Dinoprostone?What if you missed a dose of Dinoprostone?

    For informational purposes only. Consult a medical professional for advice.

    Reviewed by a panel of doctors. Source: First Databank

    Was this helpful?What does dinoprostone do to the human body? Dinoprostone is a natural substance (prostaglandin) that your body makes in preparation for labor. It softens and widens the opening of the womb and increases contractions.

    Is there a dosage form for dinoprostone? Dinoprostone is to be administered only by or under the immediate care of your doctor. This product is available in the following dosage forms: Copyright © 2021 IBM Watson Health.

    How is dinoprostone administered in the vagina? Dinoprostone comes as a vaginal insert and as a gel that is inserted high into the vagina. It is administered using a syringe, by a health professional in a hospital or clinic setting. After the dose has been administered you should remain lying down for up to 2 hours as directed by your physician.

    What are the brands of dinoprostone in the US? US Brand Name. Cervidil. Prepidil. Prostin E2.

    What happens to your body when you take dinoprostone?

    What happens to your body when you take dinoprostone? This activity may be responsible for the vomiting and/or diarrhea that is not uncommon when dinoprostone is used to terminate pregnancy.

    How does dinoprostone work in the cervix? It has important effects in labour. It also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts. As a prescription drug it is used as a vaginal suppository, to prepare the cervix for labour and to induce labour.

    What is the half life of dinoprostone hormone? Dinoprostone (PGE2) is a naturally-occurring biomolecule. It is found in low concentrations in most tissues of the body and functions as a local hormone (1-3). As with any local hormone, it is very rapidly metabolized in the tissues of synthesis (the half-life estimated to be 2.5-5 minutes).

    How does prostaglandin E2 and dinoprostone work? Dinoprostone is equivalent to prostaglandin E2 (PGE2). It stimulates labor and delivery by stimulating the uterine, and thus terminates pregnancy. Dinoprostone is also capable of stimulating the smooth muscle of the gastrointestinal tract of man.