What is cialis made out of?

Have you ever wondered what the magic pills in that iconic bathtub commercial are made out of? Look no further because this article will dive deep into the ingredients and production process of Cialis.

Introduction

Cialis, also known as Tadalafil, is a medication used to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). It belongs to a class of drugs called phosphodiesterase type-5 inhibitors (PDE-5 inhibitors), which work by increasing blood flow to certain areas of the body.

The Main Ingredient: Tadalafil

The active ingredient in Cialis is tadalafil, which belongs to a group of chemicals called cyclic guanosine monophosphate (cGMP) specific phosphodiesterase type 5 (PDE-5). This fancy terminology simply means that tadalafil inhibits an enzyme called PDE-5, which allows for increased blood flow to certain parts of the body such as the penis.

Tadalafil itself is a white crystalline powder with a molecular weight of 389.4 g/mol. Fun fact: it was discovered by GlaxoSmithKline and later developed by ICOS Corporation.

Supplementary Ingredients

While tadalafil is undoubtedly the star of the show when it comes to Cialis’s effectiveness at treating ED, there are other ingredients added during production for various purposes:

  • Croscarmellose sodium: Used as a disintegrant in tablet formulations.
  • Hydroxypropyl cellulose: Also used as a disintegrant but can also help with solubility.
  • Iron oxide: To aid in coloration.
  • Lactose monohydrate: A common filler agent found in many medications.
  • Magnesium stearate: A lubricating agent that helps prevent sticking during processing.
  • Microcrystalline cellulose: Another filler agent that helps create the tablet’s shape.
  • Sodium lauryl sulfate: A surfactant used to aid in tablet dissolution.

Production Process

The manufacturing process of Cialis is relatively straightforward:

  1. First, tadalafil and all additional ingredients are carefully weighed out using precision instrumentation.

  2. Next, these components are mixed and ground together with a mixing system such as a V-blender or double cone blender for uniform distribution.

  3. The mixture is then granulated by adding liquid binder materials until small particles form which can be dried via fluid bed drying.

  4. Afterward, the granules are screened to obtain consistent particle size before finally being compressed into tablets using high-force hydraulic press machines or rotary tablet presses depending on production capacity requirements.

Interesting Trivia Facts about Cialis

Here are some fun facts about this renowned ED medication you might not have known:

  • Unlike its competitors Viagra and Levitra, which only last 4-6 hours after consumption, Cialis can remain effective for up to 36 hours!

  • Tadalafil was originally developed as a potential treatment for heart conditions but was found more useful in treating impotence instead.

  • In addition to treating ED-related symptoms, medical professionals now prescribe low doses of Cialis as a preventive measure against prostate cancer due to its impact on blood flow regulation.

  • There is an FDA-approved version of tadalafil called Adcirca used specifically for pulmonary arterial hypertension rather than ED/BPH treatment!

In conclusion, while it may seem like magic coming from those iconic his-and-hers tubs full of rose petals we’ve all come to know so well; it turns out that there’s real science behind what makes Cialis tick! Understanding the star ingredient – tadalafil – along with all the other key players involved during manufacture presents an adventure in scientific inquiry like no other drug could hope rivaling – or brings us one step closer to reversing the ageing process – a girl can dream.

Cialis might not always seem like the most glamorous medication, but with a better understanding of what’s inside those pills, we might appreciate them (and our swimming trunks) just a little bit more.

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