What is angiotensin 2 receptor blocker?

If you’ve ever been on medication for high blood pressure or heart failure, chances are you’ve come across angiotensin 2 receptor blockers (ARBs). While the name might make it sound like a love interest from a romance novel, ARBs actually help to control your body’s blood pressure by blocking the action of a hormone called angiotensin II. In this article, we’ll delve deeper into what exactly this drug does and why it’s so important.

The Lowdown on Blood Pressure

Before we get started talking about ARBs, let’s take things back to basics with some key facts about blood pressure:

  • Your blood pressure refers to the force that your heart exerts as it pumps blood around your body.
  • It’s measured in millimeters of mercury (mmHg), with two numbers representing systolic (when your heart beats) and diastolic (when your heart rests) readings.
  • A normal reading is considered to be around 120/80 mmHg or lower. High blood pressure starts at around 140/90 mmHg.
  • Hypertension can increase the risk of stroke, heart attack and kidney disease.

Now that we’re all up-to-speed on what exactly we’re dealing with here – let’s talk about how ARBs fit into all of this!

Blocking Out Angiotensin II

So now that you understand more about how important maintaining healthy levels of blood pressure is – let us introduce you properly to those little life-savers known as angiotensin 2 receptor blockers.

To put things simply: our bodies naturally produce angiotensin II which stimulates certain receptors throughout our cardiovascular system including in our veins and arteries; but there are times when being stimulated beyond moderate levels may have detrimental outcomes rather than helpful ones – cue ARBs, which work to block the activation of these receptors. Essentially, they prevent angiotensin II from working on our blood vessels – this keeps them relaxed and dilated which lowers resistance in certain parts of cardiovascular system that help regulate blood pressure levels.

Angiotensin 2 receptor blockers are usually taken orally in tablet form; they start to take action within just a couple hours and can last up to 24 hours depending on the type prescribed.

How Do ARBs Help?

Now you might be wondering – how exactly do angiotensin 2 receptor blockers help lower blood pressure or alleviate symptoms associated with heart failure? Here’s what research has found:

  • By preventing narrowing or constriction of arteries: Angiotensin II is known for constricting our blood vessels, similar to when you choke down an artery after chowing down on artery-clogging McDonalds burgers. With reduced levels of said molecule, there’s more much needed “wiggle room” in your vitals’ plumbing systems! (Ew… bad analogy…)
  • By reducing fluid retention: another one of those pesky hormones produced by your body called aldosterone makes it easier for substances like salt and water to stay’day instead being flushed out through urine (diuretics). Aldosterone activity decreased as well with this drug family – double whammy!
  • Lowered risk for end-organs damage due due high BP: Target organs such kidneys, eyes and brain are less likely impacted since increased vessel fracturing/rupture risk takes a hit thanks so fewer vessel-damage-inducing factors, especially oxidative stress generated free radicals

Long term use may even assist during reduction and maintenance phases obesity reversal therapies. Endothelial dysfunction can lead tot systemic fat accumulation rendering ANG-II blocker therapeutic support aiding healthy lipid metabolism processing thus lowering lipids thereby increasing exercise benefit outcomes while reducing injuries courtesy anti-inflammatory benefits derived thereof.

Pros and Cons of ARBs

Like any medication, it’s important to weigh the pros and cons before deciding whether or not to take an angiotensin 2 receptor blocker. Here are some general considerations:

The Good Stuff

  • Help prevent heart attacks: patients with hypertension and history of a previous recent cardiovascular disease event on regimen containing this medication family experienced up to 20% reduction in unfavorable CV outcomes compared to those who were solely receiving placebo
  • Better tolerated than ACE inhibitors (ACEIs): This drug class is relatively well-tolerated when compared to another similar blood pressure and heart failure reducing agent — “ace-inhibitors.”
  • Effective for water retention issues causing edema: It provides diuretic effect by avoiding potassium loss unlike thiazide-based products.
    May have favorable effects on reversing obesity associated endothelial denigration through induced lipid metabolism processing optimization

Not So Great…but also not that bad?

  • Like with all pharmalogical agents there may be possibility of side effects such as increased risk regarding viral pneumonia, affected sleep quality systems overexpression, hepatic status indications deterioration following long-term use some may temporarily encounter slight increase in creatine kinase levels thus affecting muscle function systemically ) but overall reactions reported have tended towards mild and transient .

A personal experience found that users often expressed coughing fits after administration as one potential negative outcome – which granted aren’t too big off a deal if you’re outside decapitating begonias or hosting dinner parties where nobody ever shows up no matter how many fancy apps you offer – however people whom work retail positions where facial masks become necessary courtesy these daily symptoms can lead stress based burnout although unlikely over duration lower concentration/lack productivity takes its toll emotionally eventually.

Lastly; While some females report occasional subjective feelings fatigue despite adequate sleep onset/rest periods optimizing exercise(whether due directly affecting CNS or indirect effect via high blood pressure reduction caused thereof) seems to ameliorate this potential complication.

Are ARBs Right for You?

Like we said before: It is important to first tackle general lifestyle habits that could potentially lead to an increase in blood pressure. While medication can help, it should never be considered as the only response option – or even a first resort – if diet and exercise/lifestyle changes have not been tried with consistent adherence and implemented. But hey, maybe they’ve already done all of those things you know… combined drinking green teas made in Thailand with Indian yoga classes whilst performing BMX bike jumps on top a Twin Towered sky scraper (DO NOT TRY THAT BTW!).

If that’s the case? There are definitely pros and potential cons associated with getting yourself started on angiotensin 2 receptor blockers – but by working closely alongside your healthcare provider throughout your routine check ups and overall treatment plan (that would also include periodic BP measurement charts taken across specific timescales plus lab testing looking out for any complications from concurrent medical issues),

Only together will you two decide what becomes ideal therapy scheme optimized for each individual’s needs!

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