What causes pseudogout?

Pseudogout, also known as calcium pyrophosphate deposition (CPPD) disease, sounds like a mouthful. And trust me; it is no walk in the park either. This arthritic condition usually affects adults aged 60 and above. However, age doesn’t discriminate here because anyone can experience sharp joint pain that might indicate CPPD disease.

The good news is you’ve come to the right place if you’re curious about this mysterious health issue’s causes. If that statement seems rather arrogant or self-righteous to you, then chill out! We are just trying to be warm and hospitable while feeding your curiosity with plenty of fun facts about pseudogout.

Allow us to introduce Calcium Pyrophosphate Deposition…

First things first – let us explain what CPPD even means since using abbreviations alienates some readers (not judging). Calcium pyrophosphate crystals deposit in various tissues around your body such as cartilage or synovial fluid found naturally between joints. These rogue crystals ignite an inflammatory response within the body (the little rebels!), causing discomfort during joint movement.

But how do these pernicious tiny particles invade our bodies? Let’s dive yet deeper.

The One About Aging Gracefully… Or Not

Here comes bad news for all those yearning for youth: aging increases your risk factor for developing CPPD (shock horror!). Much like most irregular occurrences with health conditions prone to being more prevalent amongst senior citizens/older individuals – think diabetes type two – pseudogout firmly falls under that umbrella category.

So before pointing fingers at fate’s unfairness when diagnosed with this Arthritis-resembling jerk-puzzle-of-a-condition (yes we made up that term), it pays not to undermine irony and/or karma’s possible involvement in any way!

What makes the elderly specifically prone could be due to an accumulation of Calcium pyrophosphate crystals within the body, gradually affecting joints as you grow older. It’s not inevitable though! So do not let your hopes wild horses out in a bid to escape this condition.

But Wait – There’s More!

Like any other health issue (or reality show if I’m being honest), it would be unfair to strictly point one single cause for pseudogout, so here are some more contributing factors:


You might want to reel your ancestors’ history back here because genetics sometimes play a role in CPPD disease—essentially familial aggregation resulting from genetic variations predisposing an individual to calcium pyrophosphate crystal formation.

Of course, that largely varies from family histories – since there could very well have been no known cases yet occurring with an existing member. However, pedigree tracing is indeed present due to genetic risks constantly on or off the radar, creating generation-on-generation propensity at least in theory.

Medical Conditions and Diseases

Some medical conditions such as Hyperparathyroidism (which wasn’t pronounced correctly until after 27 attempts) or hereditary hemochromatosis can lead to pseudogout. Therefore diseases associated with these disorders can ripple through time leading indirectly towards CPPD development,(admittedly less exciting than a direct causal pathway but truth is always bitter).

Kidney dysfunction although sort-off non-specific and commonly seen alongside ages over sixty may likely contribute its share into occurrence. Also noteworthy are those illnesses that affect bone structure like Paget’s Disease which will bring up symptoms similar or overlapping with arthritis .

In essence; watch how you handle free-loaded drizzles of information emanating from suggested patterns of related-ness between various medical complications-as they are often spotted together following set pieces rather than necessarily directly influencing each other once.


Minimally invasive surgeries involving joint spaces e.g arthroscopic surgery undertaken for cartilage damaged cases have a reasonable potentiality to inflict harm. This may be due mainly to the creation of Calcium pyrophosphate crystals in response to acute injury.

Hence why it is essential not only post-surgery but even daily life or for one involved in physically demanding activities- the body must be treated with love and mercy, followed by rest and recovery (rolls eyes, yes that sounds rather idealistic).

We can add here that specific traumas like car accidents or injuries on account of playing sports/games will also increase risks leading up to CPPD – which means caution needs too adhered mandatorily dosed out/up.

To Summarise

There you go! We’ve covered most possible causes, though there could very well exist various minor sub-causes waiting around unseen corners… just do not blame us when finally struck by this monstrous condition!

But seriously – regular exercise regimes, eating healthy meals (with decent amounts of cruciferous vegetables), and supplements such as vitamin D/C might help keep borders enforced against invasion from calcium pyrophosphate crystal soldiers. Nonetheless; its anti-inflammatory benefits shouldn’t give any false sense/states of security, because prevention they say/preaches is better/quencherthan cure#UCwords.

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