What are the pharmaceutical preparations that require isotonicity?
Isotonicity is an important requisite mainly for parenteral aqueous-based pharmaceutical preparations. In addition, ophthalmic, nasal, auricular dosage forms together with irrigations meet such a requirement.Author: Publish Year:
Which is an example of an isotonic solution? Isotonic sodium chloride is a familiar pharmaceutical example of such a preparation. 0.9% w/v solution of NaCl has essentially the same concentration and osmotic pressure as the RBCs contents.
How is the volume of a prescription made isotonic? In this case, the prescription volume that needs to be made isotonic will be the total volume prescribed, less the volume of the isotonic ingredient. The prescription will be prepared by dissolving the drug (s) and tonicity agent in a sufficient volume of distilled water to make the solution isotonic.
Do you know how to calculate parenteral solutions and isotonicity? Knowing how to calculate parenteral solutions and isotonicity is a fundamental part of medicinal formulations – equipping you with the necessary skills to calculate the factors involved in injection calculations. When you’ve finished studying this section, take the time to review our additional pharmacy calculations articles.
How are ophthalmic solutions made isotonic and buffered? Sometimes, ophthalmic solutions need to be made isotonic and buffered to a certain pH. Isotonic buffered diluting solutions are added to the isotonic solution of a drug to produce the volume required. The method entails adding a sufficient volume of distilled water to a given amount of drug to make an isotonic solution of the drug.
What does it mean to say that two solutions are isotonic?
What does it mean to say that two solutions are isotonic? ISOTONIC. In the general sense, two solutions are isotonic when they contain the same amounts of solutes, or dissolved substances, and therefore have the same osmotic pressure. As commonly used in the medical field, though, isotonic solutions are solutions which have the same concentration of solute as the cells in the human body.
What are some examples of Isotonic solutions? An example of an isotonic solution would be saline solution or ringers lactate. A daily saline soluton can be used to help clear up the sinus cavity. Generally, these types of solutions are used in the medical field.
Is 0.9 NaCl solution isotonic? Ringer’s solution, 0.9% NaCl, and 1.3% NaHCO3 are therefore considered isotonic solutions because they distribute in plasma water and have calculated osmolarities of 309, 308, and 310 mOsm/L, respectively. Click here to know more about it. In this way, what is the osmolarity of a 0.9 NaCl solution?
When would you give a hypertonic solution? These solutions are very useful when the cells have water intoxication, when they have been in a hypotonic medium for a long time and they are swollen. Therefore, an administration of hypertonic solution causes a cellular dehydration and would be beneficial for the cell.