Is sodium hyaluronate the same as hyaluronic acid?

Are you tired of googling about sodium hyaluronate and hyaluronic acid, trying to figure out if they are the same thing? Fear not my friend! I am here to help demystify this confusing topic. Today we will look into these two components in detail and see whether or not they’re twins separated at birth.

What is Hyaluronic Acid?

Hyaluronic acid (HA) is a naturally occurring glycosaminoglycan found throughout our bodies. It acts like a sponge that can bind with water molecules up to 1000 times its weight. That’s why it’s popular for hydration-related purposes such as skincare treatments, injected fillers, joint lubrication and many more.

You may ask – If HA already happens inside our body then why should one inject or apply external supplements? The answer lies within the quantity produced vs what your body requires. Skincare products with HA work on providing an extra layer of hydration which enhances skin elasticity preventing wrinkles & fine lines whereas Fillers provide structure underneath the skin surface giving volume and lift to specific areas.

Sodium Hyaluronate: A close cousin of HA

Sodium hyaluronate (SH) is simply derived from HA molecule by adding salt chemical compound (Na+). Thank god! this doesn’t change anything related to their function because salt has negligible effects on other properties of HA except for increasing solubility making it easier for incorporation into consumer products.

Additionally, SH produces minimal inflammatory responses compared with unmodified forms due to smaller size better allowing absorption through deeper layers of skin tissue blahblahBLAHtechstuff…

Those who used both substances observe little difference unless tested under microscopic examination!

Processing techniques

In most cases available commercially both elements made via bacterial fermentation process followed by purification steps such as dialysis, ultra-filtration or dial filtration. The type of bacterial culture used and purification process varies based on manufacturer to manufacturer which slightly affects the end product.

Some companies prefer using traditional methods while others incorporate high-end technology such as microencapsulation or liposome delivery system that improves their performance, stability and functions!

Advantages & Disadvantages of Sodium Hyaluronate

In general its advantages and shortcomings are synonymous with HA except for:


  • Suitable for Oily sensitive skin due to lower molecular weight better penetration
  • Cost-effective because it requires lesser dosage than hyaluronic acid


  • Unstable in solutions having pH exceeding 7 / Overheating can cause degradation.
  • Because there aren’t many studies conducted comparing both substances adequately ‘if’ one is superior over another remains uncertain.

Now that we have documented extensive researches into SH & HA. It’s time to answer most asked question by consumers whether you should choose either one according to your preference?

The conclusion is BOTH forms offer an excellent solution for treating related intended uses officially listed by FDA regardless if they differ from each other – skincare products containing low-levels of SH, particularly beneficial treatment oilier faces avoiding excess oil buildup.

If curious about fillers consult with a doctor who specializes in aesthetic cosmetic medical procedures also understands personal needs before choosing between injectable treatments!

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