Is lipitor fat soluble?
Statin drugs include familiar names such as Lipitor and Crestor. These drugs lower total cholesterol to reduce your risk of a heart attack or stroke by targeting the liver and its role in cholesterol production. These drugs can be either fat or water soluble, denoting the substance in which they dissolve.
Which is better water soluble or fat soluble statins? Water soluble vs Fat soluble – Statins are soluble in both aqueous environments and oily environments. The solubility levels differ enough that it is possible to classify some as hydrophilic (better solubility in water) or lipophilic (better solubility in fats). atorvastatin, fluvastatin, lovastatin and simvastatin.
Can a fat soluble statin cause muscle damage? Since fat-soluble statins can easily enter the inside of the muscle cells, theoretically muscle damage should be increased with their use, as water-soluble statins do not easily get into the muscle cells. This hypothesis has not been confirmed and cases of Rhabdomyolysis, while rare, occurring about 1 time…
What’s the difference between lipophilic and hydrophilic statins? The predominantly lipophilic statins (simvastatin, fluvastatin, pitavastatin, lovastatin and atorvastatin) can easily enter cells, whereas hydrophilic statins (rosuvastatin and pravastatin) present greater hepatoselectivity.
Are there any fat soluble statins that cause Parkinson’s? Fat-soluble statins include drugs such as atorvastatin (Lipitor), fluvastatin (Lescol) and simvastatin (Zocor). “This doesn’t mean that statins are causing Parkinson’s,” Huang noted.
Which is better for you, fat or water based statins?
Which is better for you, fat or water based statins? Read more about… blogs.webmd.com/cholesterol… says that the theory is that the water-based statins (rosuvastatin, pravastatin) should have lower probability of muscle damage than the fat-based (simvastatin, atorvastatin), but that hypothesis hadn’t been confirmed as of 2008.
What are the different types of statins for muscle pain? There are 2 different classes of statins: Fat soluble and water soluble. The fat-soluble statins include Lipitor and Zocor and the water-soluble include Pravachol and Crestor.
How are lipid soluble statins absorbed into the cell? Lipid (fat) soluble statins make their way into the cell membranes, which are basically fats. But fats that are highly functional in terms of their relationship to the cells they enclose. Anything absorbed into fatty tissues is more difficult to get rid of than that absorbed into a water-based part of the cell.
What’s the difference between fat soluble and water soluble vitamins? The easiest way is to memorize the fat-soluble ones, as there are only four: vitamins A, D, E, and K. All others are water-soluble. Why is it possible to overdose on fat-soluble vitamins but not water-soluble ones? Because water-soluble vitamins dissolve in water right away.