Is duloxetine and cymbalta the same?

Celexa ( citalopram) and Cymbalta ( duloxetine) are antidepressants used to treat depression and anxiety disorders. Celexa and Cymbalta are not the same type of antidepressant (they do not have the same mechanism of action).

When should I take duloxetine? When duloxetine is used to treat generalized anxiety disorder, the pain of diabetic neuropathy, fibromyalgia, or ongoing bone or muscle pain, it is usually taken once a day with or without food. Take duloxetine at around the same time(s) every day.

How much does duloxetine cost? Generic duloxetine is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. The lowest GoodRx price for the most common version of duloxetine is around $6.90, 95% off the average retail price of $165.63.

How does Cymbalta affect depression? Cymbalta inhibits the reuptake of serotonin and norepinephrine in the central nervous system. It also increases dopamine by acting on dopamine reuptake pumps, thus increasing the diffusion of dopamine in the brain. It also decreases pro-inflammatory cytokines and increases the anti-inflammatory ones, which assist in relieving depression symptoms.

Is Cymbalta available in generic? A generic version of Cymbalta has been approved by the FDA. However, this does not mean that the product will necessarily be commercially available – possibly because of drug patents and/or drug exclusivity. The following products are equivalent to Cymbalta and have been approved by the FDA: Manufacturer: ACTAVIS ELIZABETH.



  • Important to read patient package insert& med guide
  • Immediately report to MD any thoughts of suicide.
  • Use with caution in late pregnancy, breast feeding
  • Important to read patient package insert& med guide
  • Immediately report to MD any thoughts of suicide.
  • Use with caution in late pregnancy, breast feeding
  • May make you drowsy or dizzy. Drive with caution
  • Avoid alcohol/other drugs that make you sleepy
  • MD may need to reduce the dose before you stop it.
  • Swallow capsules whole.

  • For capsule, delayed release sprinkle products : May open and sprinkle onto soft food. May open capsule. Mix into cool applesauce & swallow.
  • For capsule,delayed release products : Do not chew or crush. Tell doctor your complete medical history.

What are side effects of Duloxetine?Any warnings while using Duloxetine?Does Duloxetine interact with any drugs?Is Duloxetine contraindicated for any condition?How to use Duloxetine?What if you missed a dose of Duloxetine?

For informational purposes only. Consult a medical professional for advice.

Reviewed by a panel of doctors. Source: First Databank

Was this helpful?What are the signs of a duloxetine overdose? Overdose symptoms may include severe drowsiness, seizures, fast heartbeats, fainting, or coma . What should I avoid while taking duloxetine? Avoid driving or hazardous activity until you know how duloxetine will affect you. Your reactions could be impaired. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

Should I stop taking Cymbalta? Never double your dose to catch up. You should not suddenly stop taking this medicine. Doing so may cause unpleasant side effects, including nausea and headache. If you wish or need to stop taking Cymbalta, your doctor will tell you how to reduce your dose gradually over time.

What’s the best time of day to take Cymbalta? It depends.: The medication is generally written for daily use. Whether you take it in the morning afternoon or evening depends upon your preference. If it makes you sleepy you may want to take at night, if it seems to bother your sleep you may want to take it in the morning. It is however best to take it at the same time each day.

What is the best way to stop Cymbalta? Remember, the best way to stop using Cymbalta is to consult doctors or other medical or mental health professionals. They will help slowly wean you from the drug and help ease your withdrawal symptoms. Plus, if you experience harsh withdrawal symptoms, your medical care specialist can help you cope with them.