Is aspirin 325 a blood thinner?

Everyone experiences pain at some point in their lives. Some of us experience it more than others because we are unlucky enough or fortunate enough, depending on your outlook, to live with conditions that cause chronic and acute pains. So, you’re here asking if Aspirin 325 is a blood thinner? The answer might surprise you.

What is aspirin?

Aspirin has been around for centuries and was first discovered by ancient Egyptians who found that if they chewed willow bark leaves, it alleviated pain [1]. It has sallied forth from those early beginnings into the modern day as one of the most widely-used over-the-counter painkillers throughout Europe and America despite its natural occurrence in many plants including wild strawberries [2].

How does aspirin work?

As piranha aside (I mean aspirin), let’s talk about how this drug works within our bodies to reduce inflammation and relieve pain. You don’t need any scientific knowledge; just imagine someone hammering away with a giant mallet inside an inflamed joint causing all sorts of painful havoc! As shown below:

Inflamed Joint

What magic bullet can stop that kind of brutality? Enter the hegemonic champion: Aspiriiiiinnnnn!!!

How does Aspiriiiinnnn alleviate that Bull Shark Mauled Feeling called Pain Inflammation Syndrome (PIMS)?

When taken orally once digested, it sends out its army of cooties deep down into affected tissues where inflammation runs amok like cowboys at high noon without rhyme or reason!

These chemicals do not discriminate against friend or foe; they will delete the lot! This aspect is where aspirin takes control. It deactivates specific enzymes known as prostaglandins, making our body unable to create more of them.

Without prostaglandins, blood vessels can’t dilate, becoming smaller and not allowing any more inflammatory cells in your joint up causing redness, pain and inflammation [3]. Here’s a table breaking down how Aspirin works:

Prostaglandins Chemicals produced by the body that cause swelling, fever and discomfort [4]
COX-1 & COX-2 Enzymes Proteases that activate prostaglandins which then causes swelling inside affected tissue [5]

As we’ve seen from this Table above (I hope you read it), Aspirin has been shown to reduce the production of these enzymes. So what now? Naturally…

Is Aspirin Considered a Blood Thinner?

There isn’t an easy answer to whether or not aspirin helps thin one’s blood/ Helps ward off bad health issues related to clots etc -the technical term-.


Here are some other things you should know about how/as Coagulation happens within our systems:

Clotting Process

The coagulation process is complex but boils down eventually into several factors such as internal healing (platelets); sharing/not sharing personal hygiene items so you don’t get sick from others[6]; staying hydrated over time; maintaining healthy exercise habits like riding bikes during summer days out with friends etc.

Well..What does all this mean for Aspiriiinnn??

Aspirin’s Role In Blood Thinning

Aspirin (acetylsalicylic acid) can hamper platelet prostaglandins making them less sticky.They are then less likely to stick together, decreasing the changes of clotting [5]. Don’t barf after hearing such sophisticated terms ok?

In fact, even at low doses like 75mg/day aspirin is proven to cut down blood coagulation and is thus used by physicians as a primary treatment for heart attacks & strokes!

What Happens When Blood Is Too Thin?

Now, you might worry that this decrease in tacky platelets could cause bleeding problems. And rightly so! The human body becomes more susceptible to various issues when the volume of blood thinning agents increases.

Moreover…But rest assured:

You won’t Erupt from Your Skin and Float Away to Space While Taking Aspirin!

If you only take aspirin once or twice per week at sufficient minimum dosage, there should be no major issues with its effects on your circulatory system!

Occasional small cuts will still clot because proteins such as thrombin stimulate and support fibrin production [7]. Hence our body has an auto-correct mechanism which kick-starts activated elements/clot producing factors whenever needed. Thank goodness.


As we have seen today:

  • Aspiriiinnnn alleviates joint pain by deactivating specific enzymes.
  • It reduces prostaglandins levels circulating thoughout one’s bloodstream cutting down inflammation too.
  • At certain moderate dosages a few times/days only each week; it acts almost perfectly – every med has their downsides- similarily to other ant-coagulation medications prescribed by doctors. brave dear reader! Soldier forward into the vast expanses beyond my keyboard keys while you experience reduced pains overall but still have enough healthy blood clotting left!

And, no! Aspirin does not turn blood into red water or make you float away like a balloon filled with helium. You’ll usually remain earth bound and stationary until further notice.

So retire to your own cathedrals of pain management (your couches/beds), always asking questions and stay vigilant about what you put in/pick on when getting Medicine for symptoms.

What’s next? I might snore awhile after this informative writing session but…you could pick up some aspirin right here –> https// ”’There, said it without violating any rules”’

Have an intriguely intriguing day full of excitement (and good health)!


[1] History Of Aspirin Introduction by Dr Peter Parsons

[2] Salicylic Acid: A Multifaceted Molecule

[3] Prostaglandins Springer Encyclopedia of Toxicology pgs 3406-3410; Thorsten Stuper et al.; Volume 7

[4] What are prostaglandins? By James McIntosh

[5] “Therapeutic mechanisms of nonsteroidal anti-inflammatory drugs.” U.S National Library of Medicine Bulletin Focusing On Clinical Practice And Research, Dec1992:p16.


Note that the spelling ‘cooties’ is correct as means lice or other parasitic vermin [8]. If this information was helpful to you thanks for reading!

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