How to treat phototoxic reaction?

Topical corticosteroids and cool compresses may alleviate drug-induced photosensitivity. The use of systemic corticosteroids should be reserved for the most severe cases. If sunscreens are not the cause of the photosensitivity, they should be used liberally.

What drugs cause photosensitivity? There are many drugs that may cause photosensitivity. Chemotherapy drugs commonly associated with photosensitivity include: dacarbazine (DTIC-Dome®) fluorouracil (5-FU) methotrexate vinblastine (Velban®)

How long does phototoxicity last? It varies, but most doctors agree 2 months or more from day you stop taking it.You not only burn easily, what is worse, you may develop melasma , brown patches , mostly on the face, but on the body. I checked my drug books for this drug and patient teaching.

What is phototoxic effect?


  • Phototoxicity. Patients with phototoxic reactions initially have an exaggerated sunburn-like reaction with erythema, tenderness, mild to moderate swelling, and, in severe cases, blistering.
  • Polyketides and Other Secondary Metabolites Including Fatty Acids and Their Derivatives. Ulrich Matern,
  • Photoallergens