How metformin work?

Are you tired of feeling like a guinea pig every time your doctor prescribes new medication to resolve any medical condition? I mean, taking medicine without knowing how it works is just plain weird. What are the side effects and what’s happening inside our bodies that makes us feel better or recover from whatever ailment we’re facing?

Today, in this article, we’re going to dive into one such medication: Metformin – a drug used primarily for managing Type 2 Diabetes. But let me tell you, metformin is no ordinary pill. It has some unique features that make it stand out.

If someone randomly were to ask you about how one can regulate glucose levels in blood, would you have an answer ready? Because the miraculous thing about metformin is that despite it being widely used by people diagnosed with type 2 diabetes to reduce insulin resistance and manage their blood sugar levels; its core mechanism of action remains unknown. That’s right! No human knows exactly how it works yet.

So with all those miles we’ve walked together so far towards understanding anything close to how drugs work in the body- “what does this invisible superhero do?”

Suppressing Gluconeogenesis

Gluco-who now?! ‘Supressing gluconeogenesis’ simply means lowering glucose production within the liver. The liver sometimes produces too much glucose which infuses itself into our bloodstream leading causing elevated glucose levels in Diabetic individuals- but when faced against metformin GGWP (good game well played) as it decreases both:

Hepatic(Gluconeogenic) activity 

Pretty neat!

Increasing Insulin Sensitivity

Imagine waking up one morning optimistic because your clothes fit better than they did three weeks ago..Nah not today Melissa seems unrealistic but you get the drift right? Well, metformin can make it a reality. You see, without adequate insulin sensitivity whatever sugar level reduction there is will remain stalled- rendering all our fasting glucose tests useless.

By increasing Insulin Sensitivity anyone with type 2 diabetes using Metformin can answer those last months of ‘what lifestyle changes have you made to your diet’ honestly 🙂

Delaying Intestinal Absorption Of Glucose

To us, non-medical folks or people more interested in arguments than science, delaying intestinal absorption may seem like an over-the-top hyperactive brain’s irrational slogan- for medicine advocates and researchers; its music to their ears. Captivating music! Amazingly only one word fits this function correlation:


Metformin suppresses the genes which impair and slow down glucose intake by intestinal cells making sure that ample time is taken so as to avoid accumulation within hormone-secreting glands such as pancreas while also ensuring post prandial (post-meal) blood sugar levels does not skyrocket.

As we’ve gone through earlier on -type two diabetics require regulation in insulin production & proper use(Insulin Resistance). But they’re far from alone when it comes to using Metformin – Take a look at who else prefers this product;

1.Gestational Diabetes – A form prevalent during pregnancy relating around elevated blood sugars after some weeks into pregnancy.

2.PCOS(Polycystic Ovary Syndrome ) -an endocrine disorder especially seen among reproductive aged women causing infrequent ovulation due to hormonal imbalances.

3.With Obesity And Insulin Resistance History- primarily because Metformin helps with weight loss too!

4.Type 1-Diabetes sometimes uses off-label dosage-thus be extremely careful as most adults/peers would frequently assume being diabetic means same identical usage scenarios.
This table below shows the conditions Metformin target’s their prescribed cure.
Glucose regulation category Ailment Target group
Type 2 Diabetes Mellites Adults/senior citizens,Gestational Diabetes(1)
Increase insulin sensitivity PCOS Women aged between -18-50 years (Reproductive age)
Obesity and Insulin resistance history

Being able to expand the application of a medication towards other symptomatic cures requires huge amounts of care,safety checks,trial runs before being approved to market.Only then they can adjust dosages into recommended protocols knowing what possible side effects may exist on wider audience intake

And so it was with metformin!

In your medicine cabinet surrounded by things that guarantee an improved life how safe is Metformin? Well firstly about a few hundred million hypoglycemics users take it annually around the world-isn’t proof enough? But allowing for individual variations in response capabilities several industry-published studies indicate;

1.Unlike most oral diabetes formulations metformin is less prone to causing weight gain unlike some similar medications out there.

2.Metformin has been appraised as having minimal risks when used properly as advised from people knowledgeable in medical science.

3.Major safety areas include Vitamin B12 deficiency or inadequate breakdown & release metabolism levels during consumption but this usually improves over time…

4…Unless you suffer from liver damage or heart ailments; maybe allergies that dictate avoiding certain ingredients weighed heavily on daily supplements perhaps, always seek out professional advice if adding any drug onto diet/course treatment plan is suitable

If you’ve ever experienced high blood sugar levels where Diabetic risk factors loom close by-The sudden jolt back down to range normalcy often happens only after realizing lifestyle changes don’t provide respite….Metformin could be the solution to all that.

However, being someone with mild symptoms and random episodes or even taking for a condition other than Diabetes as mentioned in previous headlines such as PCOS requires proper supervision from medical care provider.

Take note of possible side effects whilst equally understanding top benefits according to your usage scenario relative only to doctor’s approval-your opinion alone is not enough despite this funny humane article’s charm 😉

Until we meet again enlightened I pray-Stay safe out there!