Does atropine slow heart rate?
If you’re wondering whether atropine is going to slow down your heart rate or not, then get ready for a wild ride because we’re about to dive deep into this topic. Atropine is a medication that has been used for years in the medical field, and its effects on the human body can be quite interesting. So without further ado, let’s see what atropine has in store!
What is Atropine?
Before delving into how atropine affects the heart, it’s important to understand what exactly this drug does. At its core, atropine is an anticholinergic drug that works by blocking acetylcholine receptors throughout the body. In normal speak: it’s designed to reduce activity of the nervous system.
The History of Atropine
At first glance, one may think that ‘atropa’ means something (maybe some ancient herb), but actually it refers to a female goddess from Greek mythology who was clearly aggressive. Well done Greeks!
Anyways moving back to our topic – history gives us insights; as early as 350 B.C., humans were using belladonna plants (which contain high amounts of alkaloids including atropines) for medicinal purposes like anesthesia during surgery.
How Does Atrophie Work on Heart Rate?
So with all drab academia out of way let’s cut through with something juicy – we want to know if antagonizing muscarinic receptors will lead our hearts closer towards Yama/ Hades using mortal terminology.
Exploring Muscarinic Receptors
Before getting technical and scientific with how it alters heartbeat rhythm – I think most people would love understanding why these Receptors are called Muscarinic? Well folks here’s where history comes back again because they were named after mushroom extracts such as muscimol being tested on intoxicated rodents which led to characteristic ‘muscarine’-like bodily spasms.
But today they are known as a specific subset of acetylcholine receptors that bind with muscarine and stimulate the parasympathetic nervous system. In plain English – they control those nerves that work to slow down most processes in our body such as heart rate, digestion or even arousal (wink wink)… oh sorry got carried away!
Atropine’s Effect on Muscarinic Receptors
The big question is,since atropine works by blocking these muscularic receptors- What happens then? Simple: it cancels out the effects caused by over-stimulating cholinergic activity.
Thus, when atropine enters your bloodstream, it can block these muscarinic receptors around the heart muscle; this causes an increase in heart rate due to reduced vagal tone(here course students may say – stand corrected! I need help!).
So basically folks what happens here is atropine cancels out all those inhibiting signals telling your heartbeat be leisurely and voila!! You have increased HR (Heart Rate).
Clinical Use of Atropine To Fight Bradycardia
Yes you’re right Bradycardia
means opposite (or reclining) i.e slower cardiac rates than normal. And indeed Atropinie has emerged as one of its clinical antidotes because if not treated promptly BRADYCARDIA may lead onto something terrifying like deadly Arrhythmic events,Ughh!
The Mechanics in Hospital Settings
For patients suffering from bradycardia conditions during hospitalization – doctors prescribe avocados until further notice; JK! Have some more Atrophiee , okay but seriously jokes aside docs will inject IV doses of Atropeen directly into their veins.. Sad thing though it doesn’t always work perfectly (just like my plans for assembling the Avengers to fight off Thanos-NO SPOILERS) but still we pursue with hope in our hearts.
Possible Side Effects
Wondering what’s The Catcher In The Rye? Well, even though atropine is generally considered a safe drug some side effects such as flushing or dryness of mouth/eyes may occur. Some patients also experience palpitations and dizziness because their heart suddenly speeds up after receiving Atophieheiaehae-ei doses.
Atropine Role in Saving Lives
Antagonising muscarinic receptors seems pretty mundane until it saves lives during emergencies.
Cardiovascular Resuscitation
If somebody experiences cardiac arrest; paramedics, nurses or doctors may opt for multiple IV injections of YATROPINON SKldhfaeanmouwfdh(fancy chemical name) into that person’s bloodstream very quickly i.e bolus intravenous dosage over few minutes followed by continuous infusion, most probably via breathing tubes so that helpful Muscles inducing responsive vibrations can happen… sounds freaky when I think about hoomans possessed by machines! Ahem!
So why do they choose as part of resuscitative efforts? Because it works – after all cause-death will not abide rules especially while killing people using sudden drop in Heart rates and causing shock; Yikes!!!
It Works on Other Organs Too!
As fun factoid did you know… Besides its uses for bradycardia relief; atrophinee is also used for various other purposes including dilating pupils before ophthalmologic examinations or reducing mucous production & secretion to cure asthma symptoms?(wow this turned into an infomercial).
Plus if being chased by kangaroo or those fashionably late zebras fleeing from your safari vehicle,and you happen to be allergic to quinine then turn towards atropiiiinee pilllls because it has anti-spasmodic properties; people have reported relief from urinary urgency as well!
Used by Athletes to lead to enhanced performance
Hold tight fellas: apparently some athletes believe that atropine could enhance their performance in sports like shooting or archery due to its ability of reducing tremors and increasing concentration without necessarily raising HR much(Gym rats – beware! the kill-joy doping testers can identify this too!)
Conclusion
Well folks, if you have made it till here then congrats!, your attention span rivals that of ‘Eveready Bunny’.. we’re sorry for leaving our sense (and modesty) behind but I hope we were able to educate (sort-of), inform between bouts of laughter today.
Before saying ‘Sayonara’ though let’s remember Atrophiehe-ei-ahaei essentially helps (in most situations) reverse unwanted side effects caused by cholinergic activity such as those leading towards bradycardia etc. Whereas in emergencies when time is precious & critical illness abounds likely my hooman counterparts will inject bolus IV doses quickly intravenously or even breathe it via tubes down patients throats when required.
So next time anyone asks,” hey does YATROOPIINEE decrease heart rate? “ You’d confidently say “NOPE!” cause now we know better than before( although clearly not good enough).