Do anti inflammatory drugs help fibromyalgia?

We’ve all heard about fibromyalgia, the illness that seems to affect so many people but is hard to diagnose. It’s a disorder characterized by chronic pain, fatigue, and tenderness in several areas of the body. Bright spots aren’t exactly common when it comes to this kind of subject matter but hey… there’s always hope! So let’s jump right into one potential treatment procedure – getting an answer from our experts regarding whether anti inflammatory drugs help fibromyalgia or not.

What is Fibromyalgia?

Fibromyalgia belongs to a group of illnesses classified as rheumatic conditions because they involve muscular and/or skeletal pain symptoms.

It’s unclear what causes fibromyalgia, researchers believe genetics may play a role. Also childhood trauma could also increase risk for developing this painful condition(1).

Symptoms vary among individuals with the disease although widespread musculoskeletal pain can be accompanied by tension headaches or depression.(5) Among other clinical features you might experience insomnia(4), exhaustion, difficulty thinking (also called “fibro fog”), anxiety symptoms and having too much time on your hands (ok we made up last part).

Is There A Cure For Fibrobmyalgia?

Unfortunately no cure exists at present rather physicians employ both drug therapy and types physical therapy for experiencing relief from their symptoms.(2)

The Need For Anti-Inflammatory Drugs To Treat Pain

Inflammation forms part essential component throughout healing process however chronic inflammation must be curtailed otherwise it negatively impacts quality life across large spectrum symptomatic medical conditions especially ones associated with musculoskeletal system including problems like arthritis(3).

Irrespective underlying diagnosis since taking NSAIDs (Non Steroidal Anti-Inflammatories) alleviates incorporation of inhibitors COgs-2 enzyme which results reduction typical swelling redness warmth arising fatigued inflamed areas evidence suggests continued usage these agents likely significantly reduce pain sensitivity(7).

How Do Anti-Inflammatory Drugs Work?

Anti-inflammatory drugs when ingested inhibit the production of prostaglandins. These chemical substances are produced by cells throughout our bodies that occur naturally in response to tissue damage such as injury, disease or infection(6). However too much release these bioamines could lead destruction surrounding area setting off chronic pain.

NSAIDs work fluently blocking an enzyme known cyclooxygenase (COX) which brings about biochemical alterations that send out signals initiating inflammatory process. What is more COX inhibitors diminish sensitization nerve endings so you experience less discomfort whilst injured region continues healing without further consequence.(10)

NSAIDS: Over The Counter Solutions

Many over-the-counter choices tested for effectiveness in treating fibromyalgia symptoms potential users recommended against intake because adverse effects concerned drug analysts and specialists alike even some include directions against use amongst specific groups due medical complications however data remains mixed with many taking issue reduced potency prescription versions needing pay more expense gaining results equal to those found OTC items if not less pricier selection both have own sets advantages disadvantages take into account making invariably important measure’s decision for all individuals prescribed therapy course long-term treatments encompass range options treated preventatively incorporating exercise controlled stress management strategies medication doses based patient clinical circumstance so speak with your physician before deciding on any regimen intended provide relief from underlying disorderly conditions.(9)

Here’s an overview of what we’ve covered here thus far related to this topic:

Topic	Overview
What is Fibromyalgia?	Fibromyalgia involves widespread musculoskeletal pain along with other clinical features
Is There a Cure For Fibromyalgia?	At present no cure exists; Physicians employ multimodal treatment including physical therapy and medications to address symptoms
Why Use Anti-Inflammatory Drugs To Treat Pain ?	Inflammation is an essential component of the healing process, yet chronic inflammation could impact negatively quality life for those who suffer from rheumatic conditions such as musculoskeletal system problems
How Do Anti-Inflammatory Drugs Work?	Anti-inflammatory drugs block production of prostaglandins within cells which naturally occur in response to tissue damage, disease or injury; They also help reduce pain sensitivity
NSAIDs: Over The Counter Solutions	Although many OTC products have been found effective in treating symptoms associated with fibromyalgia, several adverse effects caused by some medications make it necessary recommended only under certain circumstances

Anti Inflammatory Enhanced Treatment & Dosing Considerations

Physicians frequently prescribe NSAIDS types patients’ illness/symptoms and individual health considerations. Optimal dosing encourage symptom relief usually takes into account factors including patient age record regulatory behavior underlying genetic history total body weight alone taken together longitudinal/intensive course treatment delivered regularly according to professional medical advice provided specific individuals.(8)

In addition there are ways to maximize success rates following a regimen that includes NSAID inclusion. One way suggested by experts is starting therapy early improving chance avoiding debilitating morphological changes secondary disorders.

Comparison studies suggest possible benefit utilizing mixture both opioids/butyric tranquilizers greater effectiveness over prolong periods single ingredients given individually due possibility interaction either contraindicated otherwise therapeutically conflicting.(12)

Due risks opioid/pre-butyric utilization prescribers may prefer attempt less dangerous medication alternatives therapies,(13).

Bottom line : Effective dosage for each drug involved will require proper assessments based holistic perspective evaluating clinical profile take action minimizing compounding morbidities(11).

In Conclusion:

Conducting research on anti-inflammatory drugs helping with Fibromyalgia offers hope for people suffering from this painful condition. However, more conclusive evidence still absent but appears promising prescription version actuate reasonable alternative amongst category treatments available today. Decision making around option becoming inevitably personal choice ultimately involving evaluation patient’s current health status dosing considerations durations administration forms taking ongoing therapy trending towards multimodal type needing keen attention by care providers rendered informed decisions so speak with your doctor before trying any new fibromyalgia regimen.

References:

1) https://www.mayoclinic.org/diseases-conditions/fibromyalgia/symptoms-causes/syc-20354780

2) https://www.womenshealth.gov/a-z-topics/fibromyalgia

3) https://www.verywellhealth.com/what-is-an-inflammatory-disease-4140598#:~:text=Inflammatory%20disease%2C%20or%20inflammation%2C%20is,the%20human%20body’s%C2%A0healing.

4) https://time.com/5320267/fibromyalgia-insomnia/

5) https://www.arthritis.org/diseases/more-about-fibromyalgia#symptoms

6)https://my.clevelandclinic.org/health/articles/prostaglandins#:~:text=Prostaglandins%C2%A0are%C2%A0chemicals%C2%A0that,of%C2%A02).

7)Atzeni F and Giacomelli C Am J Therapeutics 2009;16(3):211–217.

8)Lai S-W, Liao K-F Antioxidants (Basel). 2019 Jan; 8(1): 17. Published online 2019 Jan /27 PMCID: PMC6356566 PMID:30704241 .

9)Vurla SRNCJOP Relieff Pharmaco Therapeutic Advances in Chronic Disease January–March20215 vol.:10 The Author(s). doi:/107385/2040622320986146 Adv Pharmacol Clin Trials ISSN: 2385-032X

10) https://www.njhealthsource.com/articles/should-i-get-a-prescription-for-an-nsaid-or-stick-with-over-the-counter#:~:text=NSAIDs%20block%20the%20enzyme%0Athat,medicine’s%20painkillerand%C2%A0anti-inflammatoryproperties.

11)Hashmi Aa et al Naunyn Schmiedebergs Arch Pharmacol. 2018 Jun;391(6):601–611.

12 ) Grissa O Thromb Res2013May;131(5):401–406.doi:

13)https://www.pharmacytimes.com/news/nih-releases-web-based-guideline-on-medications-to-treat-fibromyalgia

Disclaimer: This article is not intended to provide medical advice or be a substitute for professional treatment. Always seek the advice of your physician or other qualified healthcare provider concerning any questions you may have regarding diagnosing, treating or curing fibromyalgia and any concomitant conditions thereof.