Can you use santyl and calcium alginate together?

Have you ever found yourself needing to use multiple wound care products but not sure if they can be used together? Fear not, dear reader, we are here to answer the age-old question – Can you use santyl and calcium alginate together?

Let’s delve into the nitty-gritty of these two wound care products and see if they play nice with each other.

What is Santyl?

Before we dive into whether or not santyl and calcium alginate can be used in conjunction, let’s first take a closer look at what exactly santyl is.

Santyl, also known as collagenase, is an enzymatic debriding agent that helps remove dead tissue from wounds. It essentially eats away at the necrotic tissue while leaving healthy tissue undamaged.

This sounds like something out of a horror movie, but fear not! Santyl is actually incredibly helpful when it comes to treating chronic wounds such as pressure ulcers or diabetic foot ulcers.

What is Calcium Alginate?

Much like our introduction to santyl above, it would be remiss of us to suggest combining calcium alginate with another product without explaining exactly what it does first.

Calcium alginate dressings are made from seaweed-derived fibers that form a gel-like substance upon contact with moisture. This means that when placed on a wet wound bed (such as one oozing pus), the dressing will absorb excess fluid while simultaneously helping promote natural healing by maintaining moist conditions for cell growth.

The result? A happier wound environment leading toward faster healing times!

Can These Wound Care Products Play Nice Together?

Now that we understand what each product does individually let’s examine if santylandcoralinealgaflorella (a made-up name only used for comedic effect) are good bedfellows-err-bandages:

Yes, you can absolutely use santyl and calcium alginate together!

The collagenase in santyl does not interfere with the gel-forming properties of calcium alginate, so there should be no issue using both products.

However, it is worth noting that while these two wound care items won’t negatively impact each other their combined usage may lead to increased crust formation. This isn’t necessarily a bad thing and can easily be remedied through regular cleaning.

Benefits of Using Santyl and Calcium Alginate Together

Now that we have established combining the two is fine – let’s chat about why you might want to:

  • Faster healing times: As previously mentioned, calcium alginate maintains moist conditions for cell growth while santal removes dead tissue. Combining the duo helps encourage natural healing thus leading toward faster healing times.
  • Absorbs more moisture: Calcium alginate dressings are already highly absorbent but when paired with santyl which helps dissolve pus or debris results in wetter sores overall often occur less frequently.
  • Easy removal process: Since patients who tend to utilize substances such as calcuim algenate usually require check-ins on a frequent basis its critical to select effective bandages that will keep up with this routine; thankfully, since santhol gently dissolves dead tissues removing the combo bandage comes off cleanly every time

How To Apply The Product Combination

So now you know that yes indeed our dynamic duo can play nice together- but how do I apply them?

  1. Cleanse your hands thoroughly ensuring they’re completely dry before beginning
  2. Rinse your infected area (or wounds) detailing any ingredients used prior
  3. If suffering from an heavy infection site begin by placing either a foam dressing first or packing the hole if applicable within veins
    4a. Place enough dressing material over impacted regions ~ only moisturized covers needed


4b.If packaging is applied, then add the more fluid santyl with a dropper over it to cover everything. Ensure both segments have solid contact without gaps.
5. Tape sewn edges of dressing and packaging.

Each patient requires special attention based on each individual circumstance so be careful not to mix up separate instructions!

Side Effects of Combined Usage

We always wish for a happy ending but there are mild side effects present when combining both dressings:

  • Increased risk for crust formation: As previously mentioned above the homogeneous application can sometimes lead towards increased scabbing ultimately slowing overall healing times until resolved
  • Painful sensations possibly resulting from high amounts of gel growth within certain areas or too much liquid being absorbed
  • Possible skin irritation if santal is placed on an open wound site for extended periods (e.g., days).

The good news? These potential concerns are easily prevented through consistent monitoring and regulation making this bandage pairing notable by all means!


So, can you use santyl and calcium alginate together? Absolutely! Not only does combining them encourage natural cell growth eventually leading towards less time in recovery but doing so can offer great group dressing which will aid doctors visiting persistently affected patients plus their families providing ample relief down-the-line.

And most importantly – isn’t it humbling despite all our advancements as humans how we revive far-back medicines like seaweed extract that was once used as medicine during ancient Greece?!

If utilized properly keeping in mind its benefits plus combative measures these two products offer incredible assistance even under tough conditions associated with problematic wounds/skin issues helping yield premier results!