Can xeljanz cause hair loss?

Xeljanz is a medication that has been approved to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. However, there are concerns about whether or not this medication can lead to hair loss. In this article, we will delve into the facts and explore everything you need to know about Xeljanz and how it affects your hair.

What is Xeljanz?

No matter who you ask – doctor or patient – everyone agrees that life with chronic diseases like rheumatoid arthritis (RA), psoriatic arthritis (PA) ,and Ulcerative Colitis (UC) isn’t always easy. Joint swelling, inflammation of the skin or bowel lining, accompanied by poor quality of life – all telltale signs of these conditions. The good news is that treatments have improved significantly in recent years; however not every medicine comes without side effects.

So what exactly is Xeljanz? It’s a Janus kinase inhibitor used as an immunosuppressant for patients with RA and PA whereas people suffering from UC make use of it as an anti-inflammatory agent.Therefore just like any other medication under its category,it works by suppressing your immune system thereby controlling particular inflammatory pathways which flare up symptoms.However,Xejanx may interact differently depending on where precisely it binds within each person’s unique biological makeup.

Why Do People Take Xeljanz?

People take xalanx for various reasons:

  1. Relieving Arthritis Symptoms: As mentioned earlier,Xalenz slightly alters how cells signal each other during inflammation so as to ultimately decrease joint pain,tenderness,stiffness,and improve mobility.
  2. Remission induction: People living with moderate-severe active Ulcerative colitis also take advantage through reducing symptoms and inducing remission ultimately improving their health status.
  3. Preventing Damage Progression: For Psoriatic arthritis,early treatment with a combination therapy involving methotrexate,Sulfasalozine and Xeljanz can help avoid progression.
  4. When Other Treatments Fail: Numerous studies have shown Exeljanx which is an immunosuppressive drug as opposed to disease modifying anti-rheumatic drugs (DMARDs) is safe for moderate-severe RA patients gaining less effective response from other treatments.

Can Xeljanz Cause Hair Loss?

One of the potential side effects that Xeljanz may lead to include diffuse hair loss, also known as “telogen effluvium.” This type of hair loss occurs when there are more hairs shedding than usual due to an interruption in the growth cycle. However, it’s essential to note that this side effect isn’t common among users.

How Does Telogen Effluvium Work?

Telogen Effluvium affects three phases of your hair-growth cycle which include:

  1. Anagen Phase: In this phase,hair follicle cells divide rapidly,resulting in noticeable growth usually lasting between 2-6 years.
  2. Catagen Phase: Also referred to as transitional,the phase involves limited activity at the bottom part of each follicular root during sequence transition and ends once club-like structures forming around each strand prepare them for uprootinG from their nutrient source(blood vessels).
  3. Telogen Phase : It simply refers into dormant stages where they remain unresponsive and without changes lodged into scalp also termed resting period.the duration varies enough but lasts usually about 100days before shedding ultimately leading new sprouting by stem cells.Here’s where most TE occur–when something interrupts one or both processes mentioned above thereby accelerating/stopping normal tellogen activities with hair loosening/shedding away preceding subsequent replacement.

When Does Telogen Effluvium Occur?

As earlier mentioned,telogen effluvium may occur as a side effect of medication like Xalenz or maybe due to health disorders,pregnancy/childbirth stress,nutrient deficiencies or ailments such as hypothyroidism.Stress scenarios such dieting,intense physical strain,or lack of sleep extended for lengthy periods have also been known to initiate Telogen Effluvium.

How Common Is Telogen Effluvium?

Telogen Effluvium is a condition that’s typically temporary and reversible given the fact it doesn’t entail complete anagen halt.The good news is that most people who experience TE do not suffer significant hair loss.Of course, this makes sense given quite often; fewer than 30% hairs in scalp reside within tellogen phase at one time since they are actively growing all through-out their natural lifetime.Assuming only that you still retain ample active follicles,you should be able to regenerate new strands without signal trauma detection signifying permannent damage.However,it’s worth noting that some individuals might lose an extensive quantity of your head pigmentation.

Who Is Likely To Experience Hair Loss As A Side Effect Of Xeljanz?

The risk factor for experiencing hair loss while taking Xeljanz seems to be dose-dependent. People who take higher doses are more likely to encounter this side effect compared to those on smaller doses.This correlation however,is not yet backed by concrete scientific publication findings which truly explains why some small but noticeable cases exist so far.In established studies indicate doses ranging from 10-15mg taken two times daily lead virtually no perceivable difference compared with patients initiating with low dose around 5mg twice per day.Accordingly physicians supply drug information packs packaged together during prescription initiation indicating the possibility at default premises mostly confirming distributed public knowledge about drug effects.


Hair loss isn’t always easy, regardless of whether it happens naturally or as a side effect of a medication like Xeljanz. However, it’s essential to understand that this particular side effect is rare and typically reversible once you stop taking the medication.In case you start losing significant strands without apparent diagnosis,you might want to conduct medical diagnostics.Strict monitoring with periodic check-ins with your physician are crucial for unnoticeable adjustments.Your physicians might also suggest alternative treatments or lower doses in case they deem necessary.

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