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Can xeljanz cause hair loss?

23 Apr, 2023 by Dane Raynor

If you’re reading this article, odds are you’ve found yourself singing the beloved tune of Britney Spears’ “Oops…I Did It Again,” but instead of belting out “I’m Not That Innocent,” you’re crooning “What Have I Done to My Mane?” Don’t worry, we won’t judge. We’ll even let it slide that your new hairstyle looks like a mixture between a mullet and a pineapple. In fact, we already forgot what your hair looked like before! Whether you have alopecia or simply wondering if the medication is causing unusual hair shedding, here’s everything you need to know about Xeljanz and hair loss.

What is Xeljanz?

Xeljanz is an oral medication primarily used for treating rheumatoid arthritis (RA) in adults. It belongs to a class of drugs called Janus kinase inhibitors (or JAK inhibitors). Gotta love science! Essentially, these medications work by suppressing certain enzymes called janus kinases which play crucial roles in immune cell function. Suppressing these enzymes helps reduce inflammation associated with RA symptoms such as joint pain and swelling.

The Spectrum of Diseases

But wait – there’s more! While originally developed as treatment for RA specifically, research studies – one after another — began revealing somewhat surprising results indicating that Xeljanz seemed effective against other inflammatory diseases including psoriasis, Crohn’s disease colitis (also known as bowel inflammation) , among others.

How Does Hair Growth Work?

Been using Rogaine only to continue seeing strands escape from your head? Don’t give up hope just yet; TO now answer whether or not this drug can cause hair loss let us delve into how natural regrowth works first – focusing on how hairs grow!

Hairs grow from root follicles located deep within scalp skin layers where continually dividing cells differentiate (divide) into connective tissue, and stem cells mature to form keratinocytes (which contain a protein also known as keratin when combined together makes up the hair shaft). As these rapidly dividing cells reproduce the hair fiber eventually pushes through its cluster of living layered sheaths (connective tissues) which goes towards surface skin where it emerges.

How Does Xeljanz Work?

OK now that you’ve got Biology 101 sorted let’s get down to business – how does Xeljanz work to boost hair growth? Hold onto your cowboy hats ’cause this might make your head spin even more than that new hairstyle! When used for RA, it’s been discovered that Xeljanz operates by inhibiting two members within Janus kinase enzyme collective: JAK1 and JAK3. Hence helps in reducing pro-inflammatory cytokine production via T-helper-17 (a type of immune cell) actions since they commonly require one or both enzymes to signal transcription factors in their nuclei upon receiving their specific hormone signals; without either participating T-helper activities are severely curtailed.

Can You Fathom It All?

If not don’t worry just know randomly suppressing janus kinases with dogged persistency-like with Jack Nicholson from Something’s Gotta Give would never be good thing yet if restricted in skilled hands it may have some healing benefits plus avoiding dicey likelihoods such as drug interactions / side effects which could possibly result having no earthly idea what YOUR BODY thinks about them!

So yeah, helping people who suffer highly debilitating conditions almost likely outweigh any drawbacks associated here but given there seems be possible relationship between taking this medication desirous mainly due its immunosuppressant characteristics leading us checkout whether relating developments specifically concerning “hair loss” exist around use related topics indeed warrant closer examination.

Does Xeljanz Cause Hair Loss?

And finally — bicoastal readers take note — a straightforward answer to the big question! Yes, it is possible that Xeljanz could cause hair loss. According to clinical studies and anecdotal reports from doctors and patients alike (though in relationship context substantial research data available thus far tends consist case series / single-subject reviews without including very large numbers subjects due drugs highly selective nature), one common side effect of JAK inhibitors (including Xeljanz) is alopecia – or the medical term for hair loss.

A Close Examination

In fact, an FDA safety alert was issued in 2019 stating that interim trial results showed a higher rate of serious heart-related issues, cancer and deaths among RA patients taking Xeljanz compared to those on Humira (a popular non-JAK inhibitor RA drug) But this isn’t all folks – another issue with these medications involves potential increase opportunistic infections / risk neoplastic disease development mainly due their prolonged suppressive effects over normal immune function.

Incidentally aside some published papers surrounding few patients losing excessive amount (alopecia totalis or universalis) whilst choosing JAK inhibitors chance such reactions also exists within other immunosuppressants which warned about already re Product information leaflets.

The Verdict:

And now we’ve arrived at the moment of truth. While yes there have been instances where people have reported experiencing hair loss while taking Xeljanz, it’s important not to jump to conclusions too quickly. Always consult your physician before stopping any medication abruptly. Afterall ‘hair today gone tomorrow’ need not turn into reality!

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