Can i take benadryl with claritin d?

Are you suffering from allergic rhinitis, hay fever or any other allergies? The symptoms of these conditions can be quite bothersome, and it is not uncommon to turn to over-the-counter medicines for relief. If you are considering taking Benadryl and Claritin D together, then this article is for you!

Taking antihistamines – a brief introduction

Antihistamines are medications that work by blocking the action of histamine in your body. Histamine is released by certain cells in response to an allergen such as pollen or pet dander. It causes symptoms like itching, sneezing and runny nose.

There are two types of antihistamines:

  • First-generation – These were developed earlier than second-generation drugs. They tend to cause more side effects like drowsiness because they enter your brain more easily.
  • Second-generation – These have been developed more recently and cause fewer side effects due to their inability (or difficulty) in crossing the blood-brain barrier.

What is Benadryl?

Benadryl contains diphenhydramine which belongs to the first generation of antihistamines. It works mainly on histamine receptors found outside the brain which explains why it may cause sedation as one of its main side-effects.

Benadryl has been used for decades as a reliable medication against allergy symptoms such as itching, hives ,and sneezing. Doctors prescribe benadryls both alone or coupled with other OTCs when encountered with severe allergies.

Never drive after taking diphenhydramine (at least until 8 hours) as it could affect reaction time similarly drunk driving happens but without alcohol involved.

What about Claritin D?

Claritin-D,NOT TO BE CONFUSED WITH ITS COUNTERPART CLARITIN contains the active ingredients loratadine and pseudoephedrine, which together help to relieve your allergic symptoms. Loratadine is a second-generation antihistamine that works by blocking the H1 receptor for histamine while limiting its sedative side effects. Pseudoephedrine, on the other hand, is a nasal decongestant that helps reduce inflammation in the sinuses.

Make sure to ask yourself this question before taking Claritin D:
“Am I aware of every ingredient listed here?”

If you answered yes then continue reading but if not seek professional advice before commencing consumption

Can Benadryl be used without prescription?

Yes! Benadryl can be purchased both online or under-the-counter over-the-counter (OTC). Its easy availability often tempts people into consuming it frequently even for slight allergies forcing them into developing immunity to diphenhydramine [3].

One must always consult their doctor or an allergy specialist priorly since prolonged use could cause drowsiness and escalate drug tolerance causing bizzare hallucinations temporarily influencing one’s cognitive abilities rendering logical decision making difficult.

Are there any interactions between these two drugs?

In general taking more than 1 antihistamine at once should not be done without medical consultation . This holds true regardless of whether antihistamines are taken due to different types of allergies like food/seasonal/airborne or whether they differ in their classifications as first-generation (sedating)/second-generation(non-drowsy).

Combining such medications amplifies each’s effects including sedation leading to palpable lethargy hence it is advised against using them simultaneously.

Although partially safer than third-party interactions consumers might experience dry mouth/dizziness/Dysphoria when combining diphenhydramine with loratadine. These responses usually follow when either
– Taking Robitussin accompained by Benadryl
– Consuming Claritin-D2 pills within 24 hours

Which one do I pick then?

Both of the products serve a different purpose in alleviating allergies. Claritin D is best taken when facing congestion alongside hay fever symptoms while benadryl provides more comprehensive relief for common allergy symptoms like Itching, Runny nose and hives etc.

It could come down to your specific needs since smaller doses minimize sedative effects but consult professionals before consuming either in parallel.

Bendaryl vs. Claritin D: Comparison Table

Benadryl (diphenhydramine) Claritin D
Type of Antihistamine First-generation antihistamine Second-generation antihistamine
Main Uses Allergic rhinitis Congestion + Hayfever
Onset Time 20-30 min 1 hour


The quick-resolution-effect offered by Benadryl may resonate among those who suffer with allergies frequently however it’s drowsiness inducing effects might appear unsatisfactory for people leading active lifestyles making them lean towards alternatives such as Claritin.

Quick Recap
Don’t mix n match especially first-gen with second-gen drugs; Each has its own pros and cons and combining the two amplifies their impact often leading to palpable lethargy.
Bottom line: Always seek professional opinions before opting to use these medications together or separately.